Expresión de búsqueda: HEPARIN-BINDING EGF-LIKE GROWTH FACTOR 
Descriptores Encontrados: 1
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Descriptor Inglés:   Heparin-binding EGF-like Growth Factor 
Descriptor Español:   Factor de Crecimiento Similar a EGF de Unión a Heparina 
Descriptor Portugués:   Fator de Crescimento Semelhante a EGF de Ligação à Heparina 
Sinónimos Inglés:   Heparin-binding EGF-like Growth-Factor  
Categoría:   D12.644.276.382.625
D12.776.467.382.625
D23.529.382.625
Definición Inglés:   An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells. 
Nota Histórica Inglés:   2015 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número del Registro:   55622 
Identificador Único:   D066257 

Ocurrencia en la BVS:
 

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